Hypersensitivity Syndrome versus Drug-Related Eosinophilia
There are some overlapping symptoms between hypersensitivity syndrome and drug-related eosinophilia. However, hypersensitivity syndrome may re-activate herpes viruses that remain dormant in the body. This does not occur with drug-related eosinophilia. Some scientists believe that hypersensitivity syndrome would be a more serious type of drug-related eosinophilia. In general, it is challenging to diagnose both conditions because their symptoms do not occur immediately. That’s why healthcare providers would not immediately make a connection between the drug you took and the symptoms you are reporting. [3]
Signs and Symptoms of Hypersensitivity Syndrome
Most drug reactions lead to immediate symptoms. However, signs of hypersensitivity syndrome typically show up 3 to 12 weeks after the drug was taken. Common symptoms include swelling of saliva glands, tender lymph nodes, facial swelling, fever, flaky or scaly skin, coma, seizures, headache, trouble moving properly, abnormal levels of white blood cells, as well as a red or pink rash without or with pus-filled bumps. These problems may subside and recur for months or years. Depending on the drug you took, specific signs can vary from person to person. Some people would notice them easily, while others may need some lab tests to make a diagnosis. [4]
