Stress
Both mental and physical stress would lead to the flareups and symptoms of rheumatoid arthritis. When you experience unexpected physical overexertion, it would lead to excessive production of stress hormones, such as adrenaline and cortisol. They might intensify your autoimmune responses and lead to the attack on the body’s joints or tissues. In addition, there is a close link between rheumatoid arthritis and emotional stress. People with depression or anxiety usually report more frequent flare-ups than those without these mental issues. While there is still no clear answer for this association, many experts believe that it might come from the responses of the immune system to these conditions. [5]
