Causes and Risk Factors of Prolymphocytic Leukemia
Most cases of prolymphocytic leukemia have no clear cause. B-cell prolymphocytic leukemia often happens as the transformation of mantle cell or CCL cell lymphoma. While it is rare for this subtype to happen as an illness on its own, the condition is not contagious and not inherited. T-cell prolymphocytic leukemia is linked to mutations or abnormal changes in the genes of T-cells, which may cause these healthy cells to become cancerous ones. Major risk factors include:
– B-cell prolymphocytic leukemia: More common in older people after 69 years old and a bit more prevalent in males than females
– T-cell prolymphocytic leukemia: More common in older people after 61 years old and a bit more prevalent in males than females [4]
