Ailments & Conditions

Myelodysplastic Syndromes Treatment

Transfusion Therapy and Chelation Therapy

Transfusion therapy, often known as blood transfusion, is a procedure of giving platelets, white blood cells, and red blood cells into the body to replace damaged blood cells during treatment or by myelodysplastic syndromes. This treatment option is suggested when the number of red blood cells is low and you have signs of anemia, such as tiredness or shortness of breath. A possible side effect of transfusion therapy is the accumulation of extra iron in the body, which would cause damage to certain organ and tissue. In these cases, iron chelation therapy can help get rid of the extra iron in the blood. [7]

If you are going to get multiple blood transfusions regularly, it may increase the risk of iron overload due to the accumulation of iron in the blood and body. If left untreated, it would cause damage to certain body organs and tissues. To reduce the risk, a doctor may suggest the use of iron chelators, which may involve an oral therapy, an infusion known as deferoxamine mesylate, and deferasirox. It is important to follow the instructions to ensure the desired effects and prevent common side effects. [8]