Monoclonal Gammopathy of Undetermined Significance
Monoclonal gammopathy of undetermined significance or MGUS is a condition which would result in active myeloma. This form involves some M-proteins or abnormal antibodies in the immune system produced by cancerous cells. However, keep in mind that MGUS does not trigger any other symptoms or signs of myeloma. It is estimated that 20 percent of people with this form develop active myeloma after 20 years. Treatments are not needed until you have some side effects, such as kidney or heart issues, bleeding, muscle weakness, as well as numbness and pain in thighs, feet, or hands. A lab test every 5 to 6 months might be needed to examine the level of M proteins or possible signs of damages in several essential organs. [3]
