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Fecal Transplant for Ulcerative Colitis: What to Know

What Is Ulcerative Colitis?

Ulcerative colitis is a type of inflammatory bowel disease that leads to sores and inflammation in the digestive tract. This condition affects the innermost lining of the rectum and colon, also known as the large intestine. Symptoms can vary, depending on the affected area and level of inflammation, and occur over time instead of suddenly. These include rectal pain, abdominal cramping, diarrhea with pus or blood, fever, fatigue, weight loss, or rectal bleeding. If left untreated, ulcerative colitis may be debilitating and would cause severe complications. There is currently no cure for this condition, but some treatment options may help manage symptoms and precipitate remission in the long run. [1]

What Is Fecal Transplant?

In a fecal transplant, stool samples, with good bacteria, are collected from one or more people and then transplanted into the gut of another one. The main goal is to recreate a balanced and diverse environment that is comprised of bacteria and healthy organisms from donors. There are different methods for stool transplantation. A common option is to make a liquid slurry from the stools of donors and then pass it through a nasoduodenal tube, which goes in the nose and then down to the small intestine. [2]