Ailments & Conditions

X-Linked Hypophosphatemia (XLH) – What to Know

What Is X-Linked Hypophosphatemia?

X-linked hypophosphatemia is a rare condition that occurs when the kidneys do not work properly to process phosphate in the blood and get rid of this electrolyte during urination. Phosphorus plays an essential role in overall health, teeth, and bone development, energy production, as well as cell structures. This genetic disease only happens in 1 out of every 20,000 individuals. Some genetic factors may be passed down from parents to children and increase the risk. X-linked hypophosphatemia is also known as XLH, familial hypophosphatemia, hereditary type I hypophosphatemia, phosphate diabetes, hypophosphatemic D-resistant rickets II, hereditary type II hypophosphatemia, or X-linked vitamin D-resistant rickets. [1]