Enlarged Spleen
You can also experience low platelets when cancer spreads to your spleen and makes it become enlarged, a condition also known as hypersplenism. This organ is responsible for storing blood cells, filtering blood cells, and removing old platelets from your bloodstream. When it is inflamed, spleen would get rid of more platelets from your body than usual, resulting in thrombocytopenia.
The best way to remedy this is splenectomy surgery. During this process, your doctor will remove the spleen to prevent it from removing your platelets. However, this health issue would turn back over time, especially in those people under 40 years old. Keep in mind that your platelet counts would be abnormally high right after a splenectomy. [5]
