Precautions
Before taking imatinib mesylate, it is important to inform your healthcare provider about any other drugs you are taking. This can help prevent some possible interactions that may reduce the effectiveness or lead to serious side effects. While taking the medication, do not get any type of vaccination or immunization without the approval from your doctor. You should also talk with your doctor if you are pregnant or breastfeeding. [8]
Possible Interactions
Imatinib mesylate may interact with several foods, supplements, and other medications. This would lead to different effects, such as increased risks of side effects or reduced effectiveness of the drug. Below is a list of some medications that would interact with imatinib mesylate:
– Acetaminophen (Tylenon)
– Seizure medications, such as phenobarbital, carbamazepine, and phenytoin
– Antibiotics, such as clarithromycin
– Antifungals, such as voriconazole, ketozonazole, or itraconazole
– Opioids, such as methadone, tramadol, or oxycodone
– HIV drugs, such as saquinavir, nevirapine, or atazanavir
– Blood pressure medications, such as verapamil
– Warfarin or other blood thinners
– St. John’s wort
– Grapefruit
To reduce the risk of interactions, make sure to consult your pharmacist or healthcare provider before taking imatinib mesylate with these medications or supplements. [9]
