Ailments & ConditionsYour Health

Causes of Muscle Twitches and Spasms

Isaacs’ Syndrome

Isaacs’ syndrome, also known as neuromyotonia, is a neuromuscular disease that might trigger muscle twitches. People with this condition tend to have overactive peripheral nerve axons. It means that their nerves would send persistent signals to the muscle fibers, which causes contractions even when you are resting. Some typical signs of Isaacs’s syndrome include difficulty relaxing muscles, sweating, cramping, as well as muscle stiffness. They can vary a lot, depending on the underlying cause and overall health condition. [12]