Substance Use or Withdrawal
Seizures in adults with no history would be linked to the use or withdrawal from some substances. These may include isoniazid, tramadol, methamphetamine, cocaine, diphenhydramine, as well as antidepressants. When you take these substances, they would change the activity of neurotransmitters in the brain and cause abnormal electrical functions over time. Another explanation is that a medication or substance would modify blood flow or electrolytes in the brain. Both effects increase the risk of a seizure. Certain drugs, such as barbiturates, may have a sedative effect on your brain. When taken frequently in high dosages, a sudden stop would lead to a seizure attack. The same holds true for an abrupt withdrawal or inconsistent intake of anti-seizure drugs. [6]
