General Signs and Symptoms of De Novo Metastatic Breast Cancer
General signs of de novo metastatic breast cancer may vary from person to person. Common symptoms would include pain, sexual dysfunction, depression, insomnia, vomiting, nausea, loss of appetite, unexpected weight loss, as well as fatigue. If you experience any of these signs, make sure to talk with your healthcare provider to figure out the underlying cause and make a proper diagnosis. In most cases, the symptoms will depend on the body areas where cancer cells have spread to. In around 40 to 75% of reported cases, de novo metastatic breast cancer spread to the bones. In contrast, only 5% of reported cases affect the brain. [2]