Genetics
Familial or primary restless legs syndrome is a genetic condition. It can be heritable and nearly 65 percent of people with symptoms have a family member with this disorder. These might be children, siblings, or parents. Different genes are thought to contribute to the development of the condition through some processes linked to dopamine function in the brain and iron regulation. Sine genes identified with a higher risk of restless legs syndrome include BTBD9, TOX3, MAP2K5, SKOR1, and PTPRD. [9]
