Ailments & ConditionsYour Health

Amitriptyline to Prevent Migraine: Dose, Costs, Warnings, and More

What is Amitriptyline?

Amitriptyline is a type of tricyclic antidepressant. The FDA approved the drug in 1977 for treating depression. Currently, it is only available in generic forms. In addition to depression, amitriptyline can also be prescribed for different conditions, including chronic or migraine. Some randomized controlled trials have shown that the medication is effective in preventing a migraine attack. In fact, the United Kingdom has listed this drug as the prophylactic treatment of migraine. The cost of amitriptyline can vary, depending on how much you purchase and where you live. On average, you may expect around $25 for each prescription fill, which lasts around 44 days. [2]