Progesterone Deficiency and Estrogen Dominance in Women
In women, migraine can be influenced by various factors. It could be a menstrual cycle, menarche, menopause, use of hormonal contraceptives and hormone replacement treatment. The fluctuation of estrogen levels mediates these variations. Estrogen, the sex hormone in females, controls chemicals in the brain that affects the sensation of pains. Just before menstruation, the levels of progesterone and estrogen fall to the lowest points. This drop can trigger a headache. Migraine headaches triggered by menstruation often begins at menarche, frequently relieved during the second and third trimesters of pregnancy and eradicated a year after menopause starts. [9]
