Causes of Psoriatic Arthritis
Genetics of Psoriatic Arthritis
As said above, the exact cause of psoriatic arthritis is still not fully understood. The genes in the human leukocyte antigen complex are the most well-studied genetic factors associated with the disease. It is basically a group that helps the immune system differentiate its proteins and foreign pathogens, such as viruses and bacteria. Human leukocyte antigen genes typically have some variations, which aid the immune system to react to a range of foreign proteins. Nevertheless, some of these variations are linked with some forms of psoriatic arthritis as well as the progression and severity of the condition. [2]
