Antipsychotics and Gastrointestinal Prokinetics
Antipsychotics are prescribed to treat different medical conditions, such as anxiety disorders, Tourette syndrome, depression, Alzheimer’s disease, bipolar disorder, or schizophrenia. There are two types of antipsychotics, including typical and atypical. Examples include perphenazine, haloperidol, pimozide, promazine, chlorpromazine, or fluphenazine. They work by changing brain chemistry to reduce some psychotic symptoms, such as disordered thinking, delusions, or hallucinations. These drugs would also help prevent the recurrence of symptoms. However, certain antipsychotics may increase the risk of drug-induced Parkinsonism. [4]
Gastrointestinal prokinetics are prescription medications for treating gastric motility disorders. These are a group of digestive issues that happen when the muscles or nerves in the gut do not work in a coordinated way as usual. Gastrointestinal prokinetics work by stimulate the movement of digested food through the gastrointestinal tract. Unfortunately, some of these medications may lead to certain side effects and complications, including the increased risk of drug-induced Parkinsonism. These may include levosulpiride, prochlorperazine, or metoclopramide. [5]
