Understanding Autoimmune Hives

1What Are Autoimmune Hives?

Autoimmune hives occur when the immune system overreacts and attacks normal tissues and cells in the body instead of harmful invaders. They would happen with other autoimmune disorders or may be a stand-alone problem without any clear underlying cause. In many cases, autoimmune thyroid conditions, such as Hashimoto’s thyroiditis and Graves’ disease may frequently concur with hives. Other disorders that would be present in people with autoimmune hives may include lupus, vitiligo, rheumatoid arthritis, type 1 diabetes, celiac disease, and Sjogren’s syndrome. While autoimmune hives may be uncomfortable, they tend to be harmless. It is not simple for healthcare providers to determine the exact cause. [1]

Signs and Symptoms of Autoimmune Hives

Autoimmune hives are characterized by raised, itchy, and red bumps on the skin. The size can vary from small dots like a pinhead to big lumps. You would notice an eruption of a single or multiple hives that create a rash without a clearly defined border. When you press on the hives, the middle area will turn white. In most cases, these symptoms may be similar to those of other disorders, making it challenging to diagnose. They tend to be self-restricted and acute, disappearing after 1 or 2 days. However, chronic hives may persist for a few months or years and would be triggered by external factors, such as cold, heat, or stress. [2]


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