Experimental Drug Slows Diabetes in High-risk Kids

A recent study has invented a drug called teplizumab which would slow the breakout of type 1 diabetes in people with high risks of developing an autoimmune disease. This marks a turning point in diabetes research in the world.

On Sunday, the study was presented at a meeting of the American Diabetes Association. The results were also published in a prestigious scientific journal.

“This is an important milestone. We have had trials for several decades, but they haven’t been shown to prevent diabetes.” Said Doctor. Kevan Herold, the author of the study and professor at Yale University. “It is our first successful trial to prove that it is possible to slow and prevent diabetes.”

The study included 76 volunteers, ranging from 8 to 50 years old, who were at high risks of type 1 diabetes. 19 out of 44 people, who have randomly received the drug, developed diabetes. By comparison, 23 out of 32 participants, who had a placebo, developed diabetes.

Once the scientists stopped the study, the ratio of diabetes-free volunteers was two times as high in the drug group as in the placebo group. A low level of lymphocytes and rash were the main side effects.

The breakthrough results have excited the research community. Experts hope that it can be combined with other treatments to cure diabetes.

It is estimated that the United States has around 1.25 million people with type 1 diabetes. Among these, more than 18,000 new cases are identified each year in teenagers, who are under 20 years old. The life expectancy of those patients is shorter than other people for up to 10 years.

The current treatment options for this disease include weight loss, exercises, and healthy foods, monitoring blood sugar, and injecting insulin. The new drug, teplizumab, can slow down the development of diabetes by changing white blood cells and preventing it from killing cells that can produce insulin in your pancreases.

The drug might be most effective in the first year of treatment. Patients can delay the development of diabetes further with another therapy session.

However, there might be some hesitance to use this drug in the longer because it would throttle back your immune system excessively. This means you should use it for a short period to avoid being chronically immunosuppressed.

While most new medications are often expensive, costing around $100,000 each year. Teplizumab is worth its high expense for the proven benefits.

Source:

https://www.nejm.org/doi/full/10.1056/NEJMoa1902226

https://www.medicalnewstoday.com/articles/325430.php

Below are other symptoms that you may be interested in:

12 Signs & Symptoms of Diabetes

15 Most Common Skin Rashes

Diabetes Diet Tips – 15 Foods to Control Blood Sugar

Related Articles

Dairy and Inflammation

Food & Nutrition
Dairy is a popular part of every meal all over the world. However, many people are worried that it can trigger many inflammatory responses...

Does the Arm Pain Signal a Heart Attack? 8 Facts You Need to Know

Ailments & Conditions
As you get old, there is a variety of aches and aches your body often suffer from. While an arm pain can be a...

Torn Meniscus – Symptoms and Causes

Ailments & Conditions
Menisci are two pieces of cartilage on the knee. They work as a cushion between the thighbone and the shinbone. A torn meniscus is...

What is Bunion – 10 Facts to Know

Ailments & Conditions
What Is a Bunion? A bunion is a bony growth that develops on the joint at the bottom of the big toe. In some cases,...

Sinus Headache – Diagnosis & Treatments

Ailments & Conditions
Headaches are a common health issue that many people often experience. However, if you feel this condition with tenderness or pressure behind the noses,...

Stomach Cancer – Diagnosis & Treatment

Your Health
Stomach cancer typically starts in the stomach lining with mucus-producing cells. Also known as adenocarcinoma, this is a major cause of death in many...

Tips to Do & Avoid Before a Drug Test

Your Health
There are many reasons to take a drug test. Perhaps your job employers need the result of this procedure before they decide to hire...

10 Foods of Kidney Disease Diet

Food & Nutrition
If you are one of the patients suffering from kidney disease, then you need to know that it requires very little waste in the...