Pernicious Anemia versus Vitamin B12 Deficiencies
Many people usually confuse between pernicious anemia and vitamin B12 deficiencies. In general, pernicious anemia is an autoimmune condition that affects the parietal cells. This leads to a reduced production of intrinsic factors and a lowered absorption of vitamin B12. In some cases, pernicious anemia can be inherited as well. Some infants are naturally born with defective genes that prevent the body from making intrinsic factors.
Both vitamin B12 deficiencies and pernicious anemia may be treated effectively with an injection of vitamin B12. High-dose oral supplements can also be an option to consider for those with pernicious anemia. Since people with vitamin B12 deficiencies can still absorb B12, diet adjustments or oral supplements are enough. [7]
Diagnosis
Some tests can be done to help a doctor diagnose pernicious anemia. These include:
– Vitamin B12 level: Your doctor may measure the level of vitamin B12 with a blood test if they suspect that your anemia may be caused by a deficiency of this element.
– Parietal cell and intrinsic factor antibodies: A blood test can also check for antibodies of these cells in the stomach.
– Complete blood count: The purpose of this test is to check the levels of hematocrit and hemoglobin, which indicates the presence of pernicious anemia. [8]
