Neurological Issues
Angelman syndrome is a neuro-genetic condition. This means that the underlying genetic trigger can lead to the impairment of the peripheral and central nervous system. Thus, people with Angelman syndrome can have many signs that indirectly and directly affect movement and physiological functions. Early symptoms include motor and balance issues, making it harder to coordinate muscle movements. Their movements can be jerky with tremors in the legs and arms. In the long run, worsened muscle tone in the legs and arms would result in exaggerated reflex responses. Another typical symptom is seizures. They often first show up when the children reach 2 or 3 years old. The exact types can vary, including absence, myoclonic, and tonic-clonic. [3]
