Calcineurin Inhibitors
Calcineurin inhibitors are of 2 types – tacrolimus and pimecrolimus. These two have been proven to be very effective in treating psoriasis. These medicines inhibit the operation of calcineurin- the enzymes that activate T-cells of the immune system. Not that T-cells are bad. Just that in the process of trying to help the body fight harmful substances, the T-cells misfire and attack the skin cells causing different skin problems, including psoriasis. Calcineurin inhibitors have been proven to work for all kinds of psoriasis in children and adults. With the help of your doctor, you can select which form of calcineurin inhibitor is best for you as these medications can be given orally, injected, or used directly on the skin. [3]
